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Stress and development of depression and heavy drinking in adulthood: Moderating effects of childhood trauma

TitleStress and development of depression and heavy drinking in adulthood: Moderating effects of childhood trauma
Year of Publication2013
AuthorsColman, I., Garad Y., Zeng Y., Naicker K., Weeks M., Patten S. B., Jones P. B., Thompson A. H., and T. Wild C.
JournalSocial Psychiatry and Psychiatric Epidemiology
Volume48
Pages265 - 274
Keywordsalcohol abuse, childhood trauma, depression, epidemiology, stress
Abstract

{Studies suggest that childhood trauma is linked to both depression and heavy drinking in adulthood, and may create a lifelong vulnerability to stress. Few studies have explored the effects of stress sensitization on the development of depression or heavy drinking among those who have experienced traumatic childhood events. This study aimed to determine the effect of childhood trauma on the odds of experiencing depression or heavy drinking in the face of an adult life stressor, using a large population-based Canadian cohort. METHODS: A total of 3,930 participants were included from the National Population Health Survey. The associations among childhood trauma, recent stress and depression/heavy drinking from 1994/1995 to 2008/2009 were explored using logistic regression, as were interactions between childhood trauma and recent stress. A generalized linear mixed model was used to determine the effects of childhood trauma and stressful events on depression/heavy drinking. Analyses were stratified by sex. RESULTS: Childhood trauma significantly increased the odds of becoming depressed (following 1 event: OR = 1.66; 95%CI 1.01, 2.71; 2+ events

URLhttp://www.ncbi.nlm.nih.gov/pubmed/22684339
DOI10.1007/s00127-012-0531-8
Document URLhttp://link.springer.com/article/10.1007%2fs00127-012-0531-8