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Factors associated with plasma concentrations of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (p,p'-DDE) in the Canadian population

TitleFactors associated with plasma concentrations of polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (p,p'-DDE) in the Canadian population
Year of Publication2018
AuthorsSingh, K., Karthikeyan S., Vladisavljevic D., St-Amand A., and Chan H. Man
JournalInternational Journal of Environmental Health Research
Volume15
Pages1 - 22
Keywordsbiomonitoring, canada, chms, dde, pcbs
Abstract

This study describes blood plasma concentrations of PCBs and p,p'-DDE in the Canadian population aged 20-79 years. PCBs and p,p'-DDE were measured in 1668 participants in the Canadian Health Measures Survey, Cycle 1 (2007-2009). We investigated how concentrations vary by sociodemographic, anthropometric, and lifestyle variables, identified factors associated with exposures, and evaluated concentrations against health-based guidance values. Congeners of PCB most commonly detected were PCB-138, PCB-153, and PCB-180. p,p'-DDE was detectable in > 99% of the samples. Factors associated with [SUM]PCBs were age, region of birth, frequency of fish consumption, and liver intake (R2 = 58.1%). For p,p'-DDE, significant factors were sex, age, region of birth, household education, and ethnic origin (R2 = 47.0%). PCB concentrations in Canadians were similar to those in the United States, and lower than those reported in Europe. A small percentage equalled or exceeded the Human Biomonitoring value of 3.5 ug/L for PCBs. Few exceedances of the p,p'-DDE biomonitoring equivalent were observed.

URLhttps://www.tandfonline.com/doi/abs/10.1080/09603123.2018.1543799
DOI10.1080/09603123.2018.1543799
Document URLhttps://www.tandfonline.com/doi/full/10.1080/09603123.2018.1543799