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Development and validation of a population based risk algorithm for obesity: The Obesity Population Risk Tool (OPoRT)

TitleDevelopment and validation of a population based risk algorithm for obesity: The Obesity Population Risk Tool (OPoRT)
Year of Publication2018
AuthorsLebenbaum, M., Espin-Garcia O., Li Y., and Rosella L. C.
JournalPLoS ONE
Volume13
Pages1 - 11
Keywordsbody mass index, childhood obesity, diabetes mellitus, ethnicities, forecasting, instrument calibration, obesity, public and occupational health
Abstract

Background Given the dramatic rise in the prevalence of obesity, greater focus on prevention is necessary. We sought to develop and validate a population risk tool for obesity to inform prevention efforts. Methods We developed the Obesity Population Risk Tool (OPoRT) using the longitudinal National Population Health Survey and sex-specific Generalized Estimating Equations to predict the 10-year risk of obesity among adults 18 and older. The model was validated using a bootstrap approach accounting for the survey design. Model performance was measured by the Brier statistic, discrimination was measured by the C-statistic, and calibration was assessed using the Hosmer-Lemeshow Goodness of Fit Chi Square (HL chi-square). Results Predictive factors included baseline body mass index, age, time and their interactions, smoking status, living arrangements, education, alcohol consumption, physical activity, and ethnicity. OPoRT showed good performance for males and females (Brier 0.118 and 0.095, respectively), excellent discrimination (C statistic => 0.89) and achieved calibration (HL chi-square

URLhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191169
DOI10.1371/journal.pone.0191169
Document URLhttps://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0191169&type=printable