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The burden of breast cancer in adult women with congenital heart disease

TitleThe burden of breast cancer in adult women with congenital heart disease
Year of Publication2018
AuthorsCohen, S., Liu A., Guo L., and Marelli A. J.
JournalArchives of Cardiovascular Diseases Supplements

Background Breast cancer (BC) is the most common cancer among women in Quebec. Screening plays an important role in reducing its burden. BC incidence in adult women with congenital heart disease (ACHD) has not been studied. Aim To compare ACHD women BC incidence rates to general population. To assess if ACHD women have comparable BC screening rates to non-ACHD women. Methods The Quebec CHD database which includes 84,498 CHD patients was used to calculate the incidence rate of BC among ACHD women in 1992-2009. Age-specific and cumulative incidence of BC were calculated. The age-standardized incidence rate ratio (ASIR) was also calculated using direct standardization to compare rate to the general population and for 4 periods of time. Yearly BC screening participation rate was measured from 1989-2009, as the percentage of screen-eligible women, aged 50-69, who completed at least one mammogram within the 24 months. We compared it to the rate in Quebec general population. Results The incidence rate of BC progressively increased with advancing age with 21% of cases